Panic surges through a Heathrow-bound Boeing 747 as some passengers and crew vanish, along with millions worldwide. Captain Rayford Steele fights to quell hysteria while facing personal tragedy—his wife and son are among the missing. Rumors fly, and fanatics warn about the end of the world. Could they be right? Meanwhile, crack journalist Cameron “Buck” Williams, on the trail of a global financial conspiracy, finds a more ominous story unfolding as storm clouds of good and evil gather.